Semaglutide and tirzepatide were first used to help type 2 diabetes patients regulate their blood-sugar levels.
But in the past three to four years, they started being prescribed as a weight-loss aide, leading to global shortages and counterfeit products.
Both are given as weekly injections via pre-filled pens self-administered into the upper arm, thigh or stomach.
And patients generally start on a low dose, which is gradually increased.
The drugs mimic the intestinal hormone glucagon-like peptide-1 (GLP-1), which is released after eating and typically makes people feel fuller.
Tirzepatide (Mounjaro) also affects the glucose-dependent insulinotropic polypeptide (GIP) hormone, which controls metabolism and helps regulate energy balance.
The first study into weight-loss drugs has found they can significantly improve heart health, with lower levels of heart attacks, stroke, heart failure and high blood pressure.
An Essex police officer has been sacked after admitting “tragedy chanting” at Liverpool fans during a Premier League match last year.Essex police instigated
A police officer who admitted to “tragedy chanting” at a Liverpool football match has been sacked and barred from policing, Essex Police said.Sergeant Tyler
Aston Villa and Tottenham are ready to lock horns in an exciting FA Cup fourth-round clash at Villa Park this Sunday.Ange Postecogl
Leeds United has accused a section of Millwall fans of signing "vile chants" during an FA Cup tie at Elland Road.Shortly after Saturday's game, th